Captain Picard: As Captain of the Enterprise-D (and later the E), Jean-Luc Picard made first contact with 27 different alien species, including the Ferengi and the Borg, and was the main contact with the omnipotent Q Continuum.
Hugh: Formerly known as Third of Five, the Borg drone "Hugh" was found at a crash site by the crew of the Enterprise-D. Befriended by Geordi La Forge, he was later returned to his Borg cube with a new sense of individuality.