While the Avengers were off-world battling the Builders, the mad Titan Thanos launched an invasion of Earth, seeking his long-lost son, Thane. Thane was unaware of his father's identity, and lived in peace among the Inhumans until the Terrigen Mists activated his latent powers. Now, Thane must fight for his life alongside Captain America, the Hulk, and other returning Avengers to defeat Thanos.