Ultimate Spider-Man: Peter Parker is a high-school student gifted with the proportionate strength and speed of a spider. He fights crime in New York City as the hero Spider-Man, which attracts the attention of SHIELD director Nick Fury.

Ultimate Nick Fury: Nick Fury is the director of SHIELD, a global peacekeeping organization. Fury recruits the young Spider-Man to be an agent of SHIELD, and has the teen crimefighter work alongside other young heroes.