Wolverine: James Howlett's healing factor, retractable claws and enhanced senses made him the perfect candidate for the Weapon Plus program but Wolverine's decision to join the X-Men is what made him a hero.
Sabretooth: One of Wolverine's oldest enemies, the savage Sabretooth possesses the same healing factor and enhanced senses as his nemesis but without the compassion or honor - making him a non-stop killing machine.