Thanos: Resurrected as Death's new champion, Thanos the Mad Titan located the six Infinity Gems and sought to extinguish half of all life in the universe to impress Mistress Death herself. With unlimited power at his disposal, not even the Elders of the Universe could stop him...

Drax The Destroyer: Attacked by Thanos and left for dead, the spirit of Arthur Douglas was given new life by the Titan Mentor. With no memory of his past life or daughter Heather, he became Drax the Destroyer and swore to destroy Thanos at any cost.

Adam Warlock: Wielder of the Soul Gem and leader of the Infinity Watch, the artificially-created Adam Warlock's superhuman physical powers and energy-absorbing abilities make him a powerful threat to evil-doers throughout the cosmos.

Mephisto: None are more devilish than the demon Mephisto, responsible for untold death and destruction throughout history. Though powerful beyond our understanding, even the immortal Prince of Lies fell before Thanos's Infinity Gauntlet